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October 30, 2025

For most patients who undergo a total knee replacement, the surgery represents a new beginning — freedom from pain, restored mobility, and the ability to return to daily life without discomfort. 

However, as time goes by, some patients begin to experience symptoms that suggest their implant may no longer be performing as intended. Pain that reappears after years of comfort, persistent swelling, stiffness, or instability can all be warning signs. In such cases, it may be time to consider what is known as knee revision surgery.

Understanding the indications for knee revision surgery is essential for anyone who has undergone a previous knee replacement. This second procedure is more complex than the original, but when performed by a skilled specialist, it can successfully restore comfort, stability, and mobility. 

You can also learn more about your options for knee replacement.

What Is Knee Revision Surgery?

Knee revision surgery, also known as revision total knee arthroplasty (rTKA), is performed when a primary knee replacement fails or no longer provides adequate function. During the revision, part or all of the existing prosthesis is removed and replaced with new components designed to restore proper alignment, stability, and movement. 

While a primary knee replacement typically involves replacing damaged bone and cartilage with metal and plastic implants, a revision surgery must contend with more complex issues — such as scar tissue, bone loss, or infection — making it a technically demanding procedure.

The reasons for needing a revision vary widely. Some implants fail due to infection or mechanical wear, while others loosen over time or become unstable because of ligament imbalances. Whatever the cause, the ultimate goal of the revision procedure is to relieve pain, correct the underlying issue, and help patients regain confidence in their mobility.

Why Knee Revision Surgeries Are Increasing

With the growing popularity and success of knee replacements among younger and more active individuals, the overall number of revision surgeries has increased worldwide. Advances in implant design have improved durability and performance, yet implants remain mechanical devices subject to wear and biological response. High activity levels, obesity, or chronic inflammation can shorten the lifespan of a prosthesis, while infections, even years after surgery, can suddenly compromise an otherwise functional implant.

According to orthopedic research, the average knee replacement can last 15 to 20 years, but about 5–10% of patients may require a revision within that time frame. Understanding when that moment arrives is critical — and it’s where Dr. Mangino’s expertise becomes invaluable.

The Main Indications for Knee Revision Surgery

1. Implant Loosening or Mechanical Wear

Implant loosening is one of the most common reasons for revision surgery. Over time, the bond between the bone and the implant may weaken, leading to instability, pain, and difficulty walking. This type of loosening can occur even in the absence of infection, which is why it is referred to as aseptic loosening.

Patients often describe a deep, aching pain that gradually worsens, especially when putting weight on the joint. They may also feel that the knee is unstable or shifting during movement. In most cases, loosening results from long-term mechanical stress or from the body’s reaction to microscopic wear particles generated by the implant’s plastic components. These particles can trigger a biological process known as osteolysis, in which bone tissue gradually dissolves, further compromising the stability of the implant.

Left untreated, aseptic loosening not only causes discomfort but also increases the difficulty of any future revision, as bone quality continues to deteriorate.

2. Infection Around the Implant (Periprosthetic Joint Infection)

A periprosthetic joint infection (PJI) is a serious but relatively uncommon cause of knee replacement failure. It may develop shortly after surgery or years later due to bacteria entering the bloodstream from another part of the body. Once bacteria attach to the implant surface, they form a protective layer known as a biofilm, making them resistant to both antibiotics and the immune system.

The symptoms of infection can vary. Some patients experience classic signs like redness, swelling, and fever, while others only notice persistent pain or drainage from the surgical site. In chronic infections, symptoms may be subtle but progressive.

Treating a PJI typically requires a complex, staged approach. In a one-stage revision, the infected implant is removed, the area is thoroughly cleaned, and a new prosthesis is inserted in the same surgery. In a two-stage revision, the infected implant is removed, and a temporary spacer loaded with antibiotics is placed. After several weeks of infection control, a new permanent implant is inserted.
Dr. Mangino and his team work closely with infectious disease specialists to ensure each patient receives an individualized treatment plan.

3. Joint Instability or Malalignment

A successful knee replacement relies on proper mechanical balance between the implant and surrounding ligaments. When that balance is disrupted — whether due to surgical factors, ligament stretching, or component wear — the knee may feel unstable, shift during movement, or “give way.”

Instability can develop gradually, often accompanied by discomfort, weakness, or a sense of insecurity while walking. Patients might also hear clicking or clunking sounds when the implant moves abnormally. In these cases, revision surgery aims to realign the joint, replace worn components, and restore ligament balance.

Proper stability is crucial not only for comfort but also for long-term implant survival. An unstable implant accelerates wear and can lead to early failure if not corrected.

4. Stiffness and Limited Range of Motion

After a knee replacement, most patients gradually regain normal range of motion with physical therapy. However, in some cases, excessive scar tissue — a condition known as arthrofibrosis — can restrict movement and cause significant pain. When non-surgical interventions such as physical therapy or manipulation under anesthesia fail, revision surgery may be required to remove scar tissue, reposition the implant, or adjust component size to allow smoother motion.

Stiffness can have multiple causes, including improper component alignment, overstuffing of the joint, or insufficient rehabilitation. Dr. Mangino carefully evaluates each case to determine whether surgical or non-surgical treatment offers the best outcome.

5. Fracture Around the Implant (Periprosthetic Fracture)

Occasionally, a fall or accident may result in a fracture around the implant. These fractures often occur near the bone where the prosthesis is anchored and can destabilize the entire knee replacement. Patients typically experience sudden pain, swelling, and inability to bear weight. In such cases, imaging studies are crucial to determine whether the implant remains stable or needs replacement.

If the implant is still firmly fixed, the fracture may be treated with plates, screws, or rods. However, if the implant has loosened or bone loss is significant, revision surgery is necessary to replace the affected components and restore structural integrity. Such surgeries require meticulous planning, and Dr. Mangino’s background in complex joint reconstruction ensures that each step is carried out with precision and safety.

6. Bone Loss and Structural Damage

Bone loss can develop as a result of long-term implant wear, infection, or multiple previous surgeries. This condition poses one of the greatest challenges in revision knee surgery because a stable foundation is essential for a successful new implant. Techniques used to address bone loss include bone grafting, the use of metal cones or sleeves, and long-stem implants that extend deeper into the bone to provide stronger fixation.

The goal is not only to replace the implant but also to restore the joint’s mechanical axis and overall function. Dr. Mangino’s specialized training in the U.S. allows him to apply modern reconstruction methods that promote both stability and longevity.

7. Persistent Pain Without a Clear Cause

In some cases, patients experience chronic pain after a knee replacement even though X-rays and lab tests appear normal. This pain can stem from subtle mechanical issues, soft-tissue irritation, nerve damage, or unrecognized infection. Through comprehensive evaluation — including advanced imaging and diagnostic testing — Dr. Mangino identifies the source of pain and determines whether revision surgery or alternative treatments are most appropriate.

Pain should never be dismissed as a normal part of recovery years after surgery. Persistent discomfort is a signal that something may not be right, and early assessment can prevent more serious complications.

How Dr. Mangino Diagnoses the Need for Revision Surgery

Determining the right time for knee revision surgery requires careful evaluation. Dr. Mangino begins with a detailed consultation to review the patient’s medical history, surgical records, and current symptoms. A thorough physical examination assesses knee alignment, range of motion, swelling, and stability.

Imaging plays a vital role in diagnosis. Standard X-rays can reveal implant loosening, fractures, or misalignment, while CT or MRI scans provide a three-dimensional understanding of bone quality and soft tissue conditions. In suspected infections, blood tests and joint aspiration are used to confirm the presence of bacteria.

This comprehensive approach allows Dr. Mangino to identify the exact cause of failure and recommend the most appropriate surgical plan. His consultations are available both in person at Hospital H+ in San José del Cabo and virtually for international patients seeking a professional opinion before traveling.

The Knee Revision Surgery Process

Revision knee surgery is typically performed under spinal or general anesthesia. The duration of the operation depends on its complexity but usually lasts between two and three hours. During the procedure, the surgeon removes the existing implant, cleans and prepares the bone surfaces, and replaces the damaged components with new, custom-fitted ones. If there is bone loss, special materials such as bone grafts or metal augments are used to rebuild the area.

Unlike primary replacements, revision surgeries may require longer stems or specialized implants that provide additional support. Dr. Mangino ensures precise alignment using modern instrumentation and intraoperative imaging to optimize results and minimize future wear.

Once the new implant is secured, the incision is closed, and recovery begins under close supervision. Patients typically spend a few days in the hospital, where pain management and early physical therapy are initiated to encourage movement and prevent stiffness.

Recovery and Long-Term Results

Recovery from revision knee surgery requires patience and adherence to a structured rehabilitation plan. Most patients begin walking with assistance within 24 to 48 hours after surgery. The initial focus is on regaining mobility, reducing swelling, and controlling pain. Physical therapy gradually restores strength and flexibility, while regular follow-up appointments ensure proper healing.

The full recovery period can vary from six months to a year, depending on the complexity of the case. Although recovery may be slower than after a primary replacement, the long-term benefits — improved comfort, stability, and function — are well worth the effort. Patients often report significant improvement in quality of life once pain and instability are resolved.

Dr. Mangino’s patients benefit from his personalized rehabilitation protocols, which incorporate advanced pain control techniques such as ultrasound-guided nerve blocks and targeted sedation. These methods promote faster recovery and minimize the discomfort often associated with major orthopedic surgery.

Preventing the Need for Revision Surgery

While not all implant failures can be avoided, certain habits and lifestyle choices can help extend the life of a knee replacement. Maintaining a healthy body weight reduces stress on the joint, while regular low-impact exercise supports muscle strength and joint stability. Following postoperative instructions and attending scheduled follow-ups allow early detection of problems before they become serious.

Patients should avoid high-impact activities like running or jumping, which can accelerate implant wear. Instead, swimming, cycling, and walking are excellent long-term activities. Equally important is managing other health conditions — such as diabetes or osteoporosis — which can affect bone quality and healing.

Frequently Asked Questions (FAQs)

How do I know if my knee replacement is failing?

The most common signs of failure include increasing pain, swelling, stiffness, and instability after an initial period of improvement. Some patients also notice grinding or clicking sensations. If these symptoms persist, you should seek evaluation from an orthopedic specialist experienced in revision surgery.

How long does a knee implant usually last?

Modern implants can last 15 to 20 years or more, but longevity depends on several factors such as patient activity level, body weight, and bone health. Younger, more active patients may require revision sooner simply because their joints endure more stress over time.

Is knee revision surgery riskier than the first replacement?

Revision surgery is technically more demanding because the surgeon must deal with scar tissue, altered anatomy, and sometimes bone loss or infection. However, in the hands of an experienced surgeon like Dr. Mangino, risks are minimized through careful planning, sterile technique, and precise surgical execution.

What is recovery like after knee revision surgery?

Recovery typically takes longer than after the first surgery. Patients spend several days in the hospital, followed by weeks of structured physical therapy. It can take six months to a year to achieve full recovery, but pain relief and mobility improvements usually begin within weeks. Following your rehabilitation plan closely is essential for optimal outcomes.

Can I travel to Mexico for knee revision surgery?

Yes. Many international patients travel to Cabo San Lucas to receive world-class orthopedic care from Dr. Mangino at Hospital H+, one of the region’s most advanced medical facilities. The clinic provides bilingual assistance, transparent cost structures, and comprehensive coordination for patients arriving from the U.S. and Canada. The savings compared to U.S. prices are significant, without compromising quality or safety.

What are the success rates for knee revision surgery?

Success rates vary depending on the reason for revision, but studies show that between 80% and 90% of patients experience excellent pain relief and improved stability. The key factors for success include accurate diagnosis, proper surgical technique, and adherence to postoperative care guidelines.

Why Choose Dr. Gerardo Mangino for Knee Revision Surgery

Dr. Gerardo Mangino brings together medical excellence, international training, and a compassionate approach to care. After earning his medical degree from the National Autonomous University of Mexico (UNAM), he completed advanced fellowships in Adult Hip and Knee Joint Reconstruction Surgery at institutions in Indiana and Ohio, USA, training under leaders in orthopedic innovation.

Today, he practices at Hospital H+ inside Plaza Koral Center in San José del Cabo, a world-class medical facility known for its advanced technology, international standards, and scenic environment that supports recovery and wellness. His bilingual team provides clear communication and personal guidance throughout every stage of care — from virtual consultations and surgical planning to recovery and long-term follow-up.

International patients frequently choose Dr. Mangino for the exceptional value he offers: expert-level orthopedic care, cutting-edge technology, and significant savings compared to U.S. procedures — all delivered in a safe, modern setting.

Take the Next Step Toward Renewed Mobility

Recognizing the indications for knee revision surgery can make all the difference between prolonged discomfort and a full return to an active life. Whether you are experiencing persistent pain, stiffness, or instability years after a knee replacement, seeking professional evaluation is the safest path forward.

With his combination of advanced training, patient-centered philosophy, and experience treating international patients, Dr. Gerardo Mangino offers the expertise and reassurance you need. His approach goes beyond surgery — it’s about helping each patient regain trust in their body, confidence in their movement, and joy in their daily life.

If you suspect that your knee replacement may need revision, schedule a free virtual consultation with Dr. Gerardo Mangino today. Discover how expert orthopedic care in Cabo San Lucas can restore your comfort, stability, and confidence to move freely again.